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KMID : 0352720170410020222
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Journal of Ginseng Research
2017 Volume.41 No. 2 p.222 ~ p.226
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Effect of Korean Red Ginseng intake on the survival duration of human immunodeficiency virus type 1 patients
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Cho Young-Keol
Kim Jung-Eun
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Abstract
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Background: Long-term ginseng intake can increase longevity in healthy individuals. Here, we examined if long-term treatment with Panax ginseng Meyer (Korean Red Ginseng, KRG) can also enhance survival duration (SD) in patients with human immunodeficiency virus type 1 (HIV-1) infection.
Methods: We retrospectively analyzed 252 HIV-1 patients diagnosed from 1986 to 2013 prior to the initiation of antiretroviral therapy. Overall, 162 patients were treated with KRG (3,947?±?4,943 g) for 86?±?63 mo. The effects of KRG on SD were analyzed according to the KRG intake level and the length of the follow-up period.
Results: There were significant correlations between the total amount of KRG and SD in the KRG intake group (r?=?0.64, p?
Conclusion: KRG prolongs survival in HIV-1 patients, possibly by slowing the decrease in CD4+ T-cell count.
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KEYWORD
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annual decrease of CD4+ T cells, human immunodeficiency virus/AIDS, Korean Red Ginseng, survival duration
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